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KMID : 0191120140290000170
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Journal of Korean Medical Science
2014 Volume.29 No. 0 p.170 ~ p.175
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Injectable Tissue-Engineered Soft Tissue for Tissue Augmentation
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Rhee Sung-Mi
You Hi-Jin
Han Seung-Kyu
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Abstract
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Soft tissue augmentation is a process of implanting tissues or materials to treat wrinkles or soft tissue defects in the body. Over the years, various materials have evolved to correct soft tissue defects, including a number of tissues and polymers. Autogenous dermis, autogenous fat, autogenous dermis-fat, allogenic dermis, synthetic implants, and fillers have been widely accepted for soft tissue augmentations. Tissue engineering technology has also been introduced and opened a new venue of opportunities in this field. In particular, a long-lasting filler consisting of hyaluronic acid filler and living human mesenchymal cells called "injectable tissue-engineered soft tissue" has been created and applied clinically, as this strategy has many advantages over conventional methods. Fibroblasts and adipose-derived stromal vascular fraction cells can be clinically used as injectable tissue-engineered soft tissue at present. In this review, information on the soft tissue augmentation method using the injectable tissue-engineered soft tissue is provided.
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KEYWORD
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Cell Therapy, Soft Tissue, Tissue Engineering
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